Generation of quality evidence by appropriate scientific studies is the cornerstone of evidence informed health care provision. Scientific community is still struggling to find answers to age old problems, while new challenges are emerging at a pace unimaginable. Also, there are some fundamental questions are being raised about the sanctity & inclusivity of the current available evidence. So, there is a case for radical transformation of the scientific processes to make them more trustworthy and inclusive. “ERA” envisages to radically transform the way evidence is being generated